Jordan S. Orange, MD, PhD
Professor of Pediatrics
Louis G and Marybeth Pawleek Endowed Chair
Chief, Section of Immunology, Allergy and Rheumatology
Director, Center for Human Immunobiology
Director, Pediatrician-Scientist Training and Development Program
Vice Chair for Research – Department of Pediatrics
Jordan Orange is a Professor in the Department of Pediatrics at Baylor College of Medicine and Texas Children’s Hospital, where he is Chief of Immunology Allergy and Rheumatology, Director of the Center for Human Immunobiology, Director of the Pediatrician Scientist Training and Development program, and Vice Chair for Research. Prior to moving to Baylor in 2012, Dr. Orange was the Jeffrey Modell Endowed Chair of Immunology Research at the Children’s Hospital of Philadelphia and University of Pennsylvania School of Medicine. He is a graduate of Brown University where he also completed the MD/PhD program receiving his PhD in Pathobiology. Thereafter he completed pediatric residency at Children’s Hospital of Philadelphia and a clinical Fellowship in Allergy, Immunology and Rheumatology at Boston Children’s Hospital, and a post-doctoral research fellowship at Harvard in Molecular and Cellular. Dr. Orange has held a number of elected academic service leadership positions including as the chair of Basic and Clinical Immunology of the American Academy of Allergy Asthma and Immunology and is the most recent past president of the Clinical Immunology Society. He is a member of the Society for Pediatric Research and was elected into the American Society for Clinical Investigation in 2010.
Dr. Orange’s research has focused on the fundamental cell biology of intercellular immune interactions, novel causes of immune diseases as well as mechanistic insights gained from primary immunodeficiency. He has participated in gene discovery efforts and has contributed to the identification and understanding of a number novel genetic immune diseases – including most recently “Copa Syndrome”, which was recognized with the Lee Howley Sr. Prize from the Arthritis Foundation. Dr. Orange’s work has also benefited from insights gained from the biology of primary immunodeficiency and has succeeded in translating back to patients through an ongoing phase-I clinical trial and related efforts. Dr. Orange’s laboratory has been recognized for innovation in high- and super-resolution imaging of human immune cells and applying advanced cell biological technologies to human immunodeficiency. He is the recipient of the 2017 E. Mead Johnson Award, given by the Society for Pediatric Research, honoring his clinical and research achievements in pediatrics. The American Pediatric Society recognized Dr. Orange in 2015, awarding him the Norman J. Siegel New Member Outstanding Science Award and in 2009 he received the Justin Daland Prize from the American Philosophical Society for work in defining human natural killer cell deficiencies and Excellence in Patient-Oriented Clinical Investigation. Dr. Orange has trained and mentored more than 30 predoctoral, postdoctoral and graduate students over the past 10 years. Dr. Orange’s work has been continuously funded by the National Institutes of Health, and he has and published over 200 manuscripts.